A motorcyclist was seriously injured in a crash with a mini school bus on the Sunrise Highway, Suffolk police say.

The collision happened in the eastbound lanes at Exit 48 around 1:07 p.m. It closed all lanes on the roadway near Locust Avenue in Sayville. They reopened at 4:30 p.m.

The motorcyclist was hospitalized for treatment of serious injuries, police say.

Details surrounding how the crash unfolded were not immediately available. It wasn’t clear if there were children on the bus.