The Long Beach Fire Department says it was called to a home on Harding Avenue just after 4 a.m. Thursday for a fire.
The two-story house was smoking and there was heavy fire showing from the back of the attached garage.
A handful of neighboring departments responded to the fire as well.
News 12 is told two occupants refused medical aid at the scene. The cause of the fire is under investigation, although it does not appear to be suspicious.