All eastbound lanes of the Long Island Expressway are reopened following a serious three-car crash in Holtsville.

The eastbound lanes were closed for over five hours Thursday night.

Police say a Coram man hit a Hyundai, which then struck a third car near Exit 63.

A total of four people were hurt, including a Queens woman who was seriously injured.

A 2-year-old girl also suffered minor injuries.