The Centers for Disease Control and Prevention released a study Friday that shows suicides have soared nationwide over the last two decades.

The CDC reports that suicide rates have risen 25 percent in the U.S. since 1999.

It comes on the heels of two celebrity suicides. Television host and culinary explorer Anthony Bourdain was found dead in a hotel room in France Friday, and handbag designer Kate Spade hanged herself this week in her New York City home.

Organizations like the Long Island Crisis Center in Bellmore recommend looking for warning signs like isolation. They say feelings of hopelessness can be a direct link to suicidal thoughts. And experts say people can become suicidal for reasons beyond depression -- finances, anxiety and stressors can contribute.

"Hopeless language sounds like this: 'You don't get it. You don't understand. My life has been like this. It will always be like this,'" says Laura Campbell, of the Crisis Center.

Campbell says everyone should put the suicide prevention lifeline phone number in their contacts so they can help a person in crisis -- and remind that person there is help and the intense feelings they are experiencing are only temporary.

"They might be where you are in the moment, but they don't last forever," says Campbell.

Health experts say the key to prevention is talking about suicide and knowing that programs are available.