The attack on a gay nightclub in Orlando that killed 49 people has sparked, yet again, a national debate on gun control.

Amina Bradley, of Uniondale, says gun control measures should be enacted in the wake of the deadliest mass shooting in the nation's history.

"I've had enough," she told News 12.

It's a point Senate Democrats tried to hammer home Wednesday. Sen. Chris Murphy (D - Connecticut) led a nearly 15-hour filibuster overnight, demanding votes on gun control measures.

Sen. Kirsten Gillibrand (D - New York) also made her feelings known.

"No one outside of our military...needs to have access to a weapon that can fire hundreds of bullets a minute," said Gillibrand.

Presumptive Republican presidential nominee Donald Trump says he's open to considering some changes as well, tweeting, "I will be meeting with the NRA, who has endorsed me, about not allowing people on the terrorist watch list, or the no fly list, to buy guns."

Gary Hungerford, of the Suffolk Alliance of Sportsmen, said a change to gun laws will not make any difference.

"There is no way that any statute can prevent the kind of stupidity which happened in Florida, or anywhere else," said Hungerford.

House Speaker Paul Ryan says after Orlando, the primary focus should be on combatting ISIS, not gun control.